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Stress is gaining increased attention across the U.S. and globally due to its significant impact on physical and mental health. At the same time, mindfulness is emerging as a powerful, evidence-based tool for well-being, demonstrating how the simple act of self-awareness can help downregulate the body’s stress response, leading to a healthier and more fulfilling life. This presentation explores the neurobiology of stress and its effects on the brain and body, the science of neuroplasticity and our ability to rewire thought patterns, and practical, data-driven techniques to regulate the nervous system in the face of everyday and high-stakes stressors. With a dynamic blend of science, humor, and real-world application, this session will leave you thinking differently about stress, and empowered to lead your life with greater clarity, calm, and purpose.